Anti-inflammatory therapy for temporomandibular joint osteoarthritis using mrna medicine encoding interleukin-1 receptor antagonist

HIGHLIGHTS

  • who: Jia Deng and colleagues from the Department of Biofunction Research, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan have published the research: Anti-Inflammatory Therapy for Temporomandibular Joint Osteoarthritis Using mRNA Medicine Encoding Interleukin-1 Receptor Antagonist, in the Journal: Pharmaceutics 2022, 14, x FOR PEER REVIEW of /2022/
  • what: The authors demonstrated the therapeutic effects of IL-1Ra mRNA on TMJOA. While the modified mRNA may preferably be used in clinical practice, the experimental results of joint inflammation suppression, even using wild-type mRNA obtained in this study . . .

     

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