Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating picalm at the blood-brain barrier

HIGHLIGHTS

• who: Kassandra Kisler from the that we studied consistent with some previous reports in XFAD mice [54-57]Therefore, both female and male mice were used in the study. XFAD mice were crossed to Picalm+/- mice to generate PICALM-deficient XFAD mice (Picalm+/- have published the research work: Anti-malaria drug artesunate prevents development of amyloid-u03b2 pathology in mice by upregulating PICALM at the blood-brain barrier, in the Journal: (JOURNAL)
• what: The present results further underscore the importance of vascular function and Au03b2 clearance across the BBB in preventing the progression of AD . . .
  

   

  

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