Anti-osteoclast effect of exportin-1 inhibitor eltanexor on osteoporosis depends on nuclear accumulation of i κ b α – nf- b p65 complex

HIGHLIGHTS

• who: NF-κB and colleagues from the Siddharth University Kapilvastu, India have published the research: Anti-Osteoclast Effect of Exportin-1 Inhibitor Eltanexor on Osteoporosis Depends on Nuclear Accumulation of I κ B α - NF- B p65 Complex, in the Journal: (JOURNAL)
• what: Frontiers in Pharmacology | www.frontiersin.org August 2022 | Volume 13 | Article 896108 Anti-Osteoclast this study, the authors demonstrated that Elt inhibited osteoclast production and function by trapping IκBα and p65 in the nucleus and thereby inhibiting NF-κB activity and effectively reversing bone loss in ovariectomized mice.
• how: Because Elt . . .
  

   

  

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