HIGHLIGHTS
- who: Daniel Andru00e9s Osorio-Rodru00edguez from the University of Miami, United States have published the paper: Anti-ROR1 CAR-T cells: Architecture and performance, in the Journal: (JOURNAL)
- what: In this study, ROR1 was shown to promote the ability of cancer cells to migrate in Matrigel, engraft in immunodeficient mice, and survive chemotherapy. In the study conducted by Srivastava et_al to evaluate the SynNocht strategy (previously described) to avoid toxicity and death caused by ROR1 CAR-T_cells, different mouse strains such as C57BL/6J (B6), BALB/c Rag2-/-, ROR1-KO were used in the different . . .
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