Anti-septic functions of cornuside against hmgb1-mediated severe inflammatory responses

HIGHLIGHTS

  • who: Nayeon Kim and collaborators from the College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University , have published the research work: Anti-Septic Functions of Cornuside against HMGB1-Mediated Severe Inflammatory Responses, in the Journal: (JOURNAL)
  • what: The authors aimed to demonstrate the effectiveness of CN for preventing and treating HMGB1-mediated vascular integrity failure in_vitro and in_vivo.
  • how: The authors examined if CN could suppress HMGB1-induced excessive permeability and if the reduction of in response to LPS treatment increased the survival rate in a mouse model of sepsis. The . . .

     

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