Anti-tumor necrosis factor-alpha monoclonal antibody suppresses colorectal cancer growth in an orthotopic transplant mouse model

HIGHLIGHTS

• who: Takeshi Takasago and collaborators from the Department of Gastroenterology, Hiroshima University Hospital, Hiroshima, Japan, Department of have published the paper: Anti-tumor necrosis factor-alpha monoclonal antibody suppresses colorectal cancer growth in an orthotopic transplant mouse model, in the Journal: PLOS ONE of January/19,/2023
• what: The authors aimed to evaluate for the first time the effect of anti-TNFu03b1 mAb on the tumor microenvironment in the absence of intestinal inflammation in a colorectal cancer orthotopic transplant mouse model suitable for tumor microenvironment assessment. Third, this study showed significant changes in immune_responses in . . .
  

   

  

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