HIGHLIGHTS
- who: Malignant Glioma and colleagues from the Brain Tumour Research Centre, Medical School, Queens Medical Centre, University of Nottingham, Nottingham , UH, UK have published the paper: Antiangiogenic Therapy and Mechanisms of Tumor Resistance in Malignant Glioma, in the Journal: (JOURNAL) of 15/Dec/2009
- what: The authors evaluate current antiangiogenic therapies (summarized in Table 1) and mechanisms of resistance for malignant glioma and consider the development of novel methods of drug delivery to overcome the problem of achieving therapeutic drug concentrations within the CNS caused by the impermeability of the blood brain barrier (BBB).
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