Antibacterial activity and mechanism of sanguinarine against staphylococcus aureus by interfering with the permeability of the cell wall and membrane and inducing bacterial ros production

HIGHLIGHTS

• who: Yeqing Gu from the University of Pisa, Italy have published the paper: Antibacterial activity and mechanism of sanguinarine against Staphylococcus aureus by interfering with the permeability of the cell wall and membrane and inducing bacterial ROS production, in the Journal: (JOURNAL)
• what: The results of the FDA staining experiment in this study showed that different concentrations of SGCH all caused the loss of fluorescein from the intracellular bacteria, thus decreasing the fluorescence intensity of FDA, which indicated that SGCH at different concentrations could significantly damage the permeability of the SA cell membrane.
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