Antibody-based approaches to target pancreatic tumours

HIGHLIGHTS

  • who: Marie Sorbara et al. from the Centre de Recherches en Cancu00e9rologie de Toulouse, Universitu00e9 de Toulouse, Inserm, CNRS have published the paper: Antibody-Based Approaches to Target Pancreatic Tumours, in the Journal: Antibodies 2022, 47 of /2022/
  • what: This study showed this fluorescent tracer is safe and feasible to use during PDAC surgery .
  • future: Because pan-AKT inhibition can induce unwanted toxicities a more specific inhibition of AKT isoforms was achieved with nanobodies specifically targeting either AKT1 or AKT2 and it showed inhibitory effects in_vitro but additional works would be required to . . .

     

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