Antibody binding selectivity: alternative sets of antigen residues entail high-affinity recognition

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  • who: Yves NominĂ© et al. from the Grenoble, Francethe University of Strasbourg (UdS)This work used have published the Article: Antibody Binding Selectivity: Alternative Sets of Antigen Residues Entail High-Affinity Recognition, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0143374]. December 2, 2015 of July/15,/2015
  • what: The authors demonstrate that scFv1F4 recognizes with strong affinity peptides that possess alternative three-residue motifs at essential positions 11 to 13 (WT motif 11DPQ13, variant motifs 11SVF13 and 11SPF13), within a common motif (F9-Q10 and R15). The authors demonstrate that the sequence . . .

     

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