HIGHLIGHTS
- who: Takeshi Inoue and collaborators from the Human subjects and sampling Human blood samples were collected at Hakodate National Hospital, Hokkaido University, and Osaka University, and plasma and PBMCs were isolated using Leucosep Tube (Greiner Bio-One) or Lymphoprep Tube (Serumwerk Bernburg) according to the manufacturer`s instructionsThe study protocol was approved by the institutional review board of Hakodate National Hospital (permit no., ), Hokkaido University Hospital (permit no., ), Osaka University Hospital (permit no., ), and Osaka University (permit no. IFReC-2021-4-2, ). All volunteers provided written informed consent in accordance with the Declaration of Helsinki. have published . . .

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