Anticalin n- or c-terminal on a monoclonal antibody affects both production and in vitro functionality

HIGHLIGHTS

  • who: Nicolas Aubrey and colleagues from the 282, University of Tours, Monge, Tours, France have published the Article: Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality, in the Journal: Antibodies 2022, 11, x FOR PEER REVIEW of /2022/
  • what: This work seeks to understand the best position for an anticalin to fuse to an Ab format with respect to the functionality of the BsAb so formed. The authors evaluated the different positions of an anticalin on Ab shape to aninhibitors than mAbs without anticalin with anticalin positionof4 . . .

     

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