Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death

HIGHLIGHTS

  • who: Isabelle Martins from the (UNIVERSITY) have published the article: Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death, in the Journal: (JOURNAL)
  • what: Using novel multispectral imaging flow-cytometry-based methodology, the authors show that cancer cells respond to treatment with various anticancer agents by undergoing simultaneously several death modalities that can be either cell-autonomous or non-cellautonomous and are distinctly impacted by the tumorsuppressive factor p53, revealing unsuspected heterogeneity of cell death responses to anticancer treatment.
  • how: The transcriptional activity of p53 tumor-suppressor protein distinctly . . .

     

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