Anticholinergic drugs interact with neuroprotective chaperone l-pgds and modulate cytotoxicity of aβ amyloids

HIGHLIGHTS

• who: Kimberly Jia Yi Low from the School of Biological Sciences, Nanyang Technological University, Singapore, Singapore United States have published the paper: Anticholinergic Drugs Interact With Neuroprotective Chaperone L-PGDS and Modulate Cytotoxicity of Au03b2 Amyloids, in the Journal: (JOURNAL)
• what: The authors propose that these AC drugs will exhibit offtarget activity by directly interacting with the Ab peptides and modify their morphology and cytotoxicity. The authors report the effects of these anticholinergic compounds on the neuroprotective function of L-PGDS and the direct interaction of these compounds with the Ab(1-40) peptides resulting . . .
  

   

  

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