Antidepressant/anxiolytic and anti-nociceptive effects of novel 2-substituted 1,4-benzodiazepine-2-ones

HIGHLIGHTS

• who: Harjit SINGH from the School of Life and Health Sciences, Pharmacy, Aston University, Aston Triangle, Birmingham , ET, England have published the Article: Antidepressant/Anxiolytic and Anti-Nociceptive Effects of Novel 2-Substituted 1,4-Benzodiazepine-2-ones, in the Journal: (JOURNAL)
• what: By using simply refluxing oxazepam with hydrazines and hydrazides in the presence of acid novel 2-diazo-1,4-benzodiazepines were furnished, of which the diazo derivatives and 5k were highly coloured.
• how: The analgesic effect of 5k was tested in the tail flick test from 5-50 mg/kg . . .
  

   

  

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