Antidepressants promote the spread of extracellular antibiotic resistance genes via transformation

HIGHLIGHTS

  • who: Ji Lu from the (UNIVERSITY) have published the article: Antidepressants promote the spread of extracellular antibiotic resistance genes via transformation, in the Journal: (JOURNAL)
  • what: Implications to antibiotic resistance and micropollutant management the research demonstrated SNRI category antidepressant-duloxetine, SSRI category antidepressant-sertraline and fluoxetine, and NDRI category antidepressant-bupropion at clinical relevant concentration can promote the natural transformation of plasmid-borne ARGs into an opportunistic pathogen A. baylyi ADP1.
  • how: To further validate the causal effects of oxidative stress in mediating the uptake of ARGs by A. baylyi ADP1 the authors . . .

     

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