HIGHLIGHTS
- who: Sonia Bortolotti and colleagues from the RandD Department, Bologna, Italy Pediatric Oncology and Hematology Unit, IRCCS, University Hospital of Bologna, Bologna, Italy have published the research: Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance, in the Journal: (JOURNAL)
- what: The authors propose an innovative approach to MYCN inhibition by an MYCN-specific antigene-PNA oligonucleotide (BGA002)-as a new precision medicine for MYCN-related The authors show that MYCN inhibition by BGA002 is specific and highly effective in the context of MYCN-related SCLC.
- how . . .
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