Antigenic protein modifications in ehrlichia

HIGHLIGHTS

  • who: Zhou Hongyan from the DepartmentUniversity of Texas Medical Branch, Galveston, Texas, USA have published the paper: Antigenic protein modifications in Ehrlichia, in the Journal: (JOURNAL)
  • what: The authors showed that antibodies to both the avirulent E. muris and virulent IOE cross-reacted reciprocally with the other ehrlichiae and E. muris antigenic proteins had greater post-translation modifications viz., lipoylation, glycosylation and phosphorylation compared to the IOE proteins. GroEL is the predominant antigenic protein in both E. muris and IOE and the studies have shown that the protein is phospholipo-glycosylated, hence the authors hypothesize . . .

     

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