HIGHLIGHTS
SUMMARY
According to clinical practice, the treatment of periodontitis involves the mechanical elimination of the microbial biofilm that causes inflammation and/or infection (Skucaite et_al, 2010; Ardila and Bedoya-Garcia, 2020). In some cases, in addition to the mechanical debridement of infected periodontal pockets, the clinical treatment protocol for severe forms of periodontitis may involve the adjuvant use of antibiotics (Kulik et_al, 2019; Arredondo et_al, 2020). Duration of the study Nine studies reported the duration of the study (Gamboa et_al, 2013; Xie et_al, 2014; Binta and Patel, 2016; Arredondo et_al, 2019, 2020; Mínguez et_al . . .
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