Antiretroviral levels in the cerebrospinal fluid: the effect of inflammation and genetic variants

HIGHLIGHTS

  • who: Jessica Cusato and collaborators from the Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Amedeo Savoia Hospital, University of Turin, Turin, Italy have published the research: Antiretroviral Levels in the Cerebrospinal Fluid: The Effect of Inflammation and Genetic Variants, in the Journal: Diagnostics 2023, 13, 295. of /2023/
  • what: The aim of this study was to evaluate ARV penetration according to compartmental BBB permeability and single-nucleotide polymorphisms (SNPs) in drug transporter encoding genes. neopterin (ELISA) plasma and ARV concentrations (HPLC) and host in ABCC2 HNF4u03b1 SLCO1A2 and SLC22A6 (real-time PCR . . .

     

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