HIGHLIGHTS
- who: Karim Harhouri and collaborators from the Département Génétique Médicale, Institut National d'Hygiène, Rabat, MoroccoDepartement, la Timone Children's Hospital, APHM, Marseille, France have published the research work: Antisense-Based Progerin Downregulation in HGPS-Like Patients’ Cells, in the Journal: (JOURNAL)
- what: The second approach aimed to reduce Prelamin A quantities by blocking the cryptic splice site leading to Progerin mRNA production using morpholino antisense oligonucleotides (AON) . The fibroblast cell lines used belong to a biological sample collection declared to the French ministry of Health (declaration number DC-2008 . . .
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