Antisense oligonucleotides: an emerging area in drug discovery and development

HIGHLIGHTS

• who: Karishma Dhuri and collaborators from the Department of Pharmaceutical Science, University of Connecticut, Storrs, CT, USA have published the article: Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development, in the Journal: (JOURNAL)
• what: The excitement surrounding antisense oligonucleotide-based drug discovery and development had previously waned due to lack of clinical efficacy even at high ASO doses [171].
• future: The authors also discuss various promising ASO-based drug candidates in the clinical trials and the outstanding opportunity of emerging microRNA as a viable therapeutic target for future ASO-based therapies . . .
  

   

  

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