Antitumor activity and mechanism of action of hormonotoxin, an lhrh analog conjugated to dermaseptin-b2,a multifunctional antimicrobial peptide

HIGHLIGHTS

• who: Mickael Couty et al. from the Université, École Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules (LBM), Signaux Peptidiques (BioSiPe), Paris, France have published the research: Antitumor Activity and Mechanism of Action of Hormonotoxin, an LHRH Analog Conjugated to Dermaseptin-B2,a Multifunctional Antimicrobial Peptide, in the Journal: (JOURNAL)
• what: The authors report the design and synthesis of the chimeric peptide H-B2, a molecule composed of dermaseptin-B2 coupled to an LHRH analog, and studies of its structure and biological activities in_vitro and in_vivo, as well as deciphering its antitumor mechanism . . .
  

   

  

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