Antitumoral effects of bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of t cell response in vivo

HIGHLIGHTS

• who: Monica Benvenuto from the DMSO and Sulforhodamine B (SRB) were purchased from Sigma Aldrich (Milan, Italy)Bortezomib (Bor) was obtained from Selleck Chemical (Munich, Germany)., VAD-FMK was purchased by Calbiochem (San Diego, CA, USA). Antibodies against u03b3H AX, ERK, phosphoERK, p38a/SAPK2a, and p, MAPK (pT180/pY182) were obtained from BD Pharmingen (BD Biosciences, San Jose, CA, USA). Antibody against activated caspase , was obtained from Cell Signaling Technology (Danvers, MA, USA). Antibodies against Bax, Bcl-2, (F-2), AKT and phospho-AKT were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Anti-Erb, (1 . . .
  

   

  

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