Apamin structure and pharmacology revisited

HIGHLIGHTS

  • who: September and collaborators from the University of Poitiers, France have published the research work: Apamin structure and pharmacology revisited, in the Journal: (JOURNAL)
  • how: For consistency the authors used apamin purified from the honeybee Apis mellifera venom (product number A1289) and synthetic melittin (M4171) purchased from Sigma-Aldrich. The samples a non-treated control and a sterility control were tested in five independent experiments (n=5). For current measurements the authors used an internal pipette solution containing (in mM) K+ aspartate 160 MgCl2 2.08 HEPES 10 EGTA 10 and CaCl2 8.55 (1 . . .

     

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