HIGHLIGHTS
- who: Song Wu from the School Huazhong University Science and Technology, Wuhan, China have published the Article: Apical-basal polarity precisely determines intestinal stem cell number by regulating Prospero threshold, in the Journal: (JOURNAL) of February/28,/2023
- what: The authors propose a model in which the Baz/Pros ratio determines sibling cell fates: when Pros levels fall below a threshold, Baz in apical daughters maintains stem_cell fate by counteracting Pros accumulation during the first two asymmetric divisions. The authors propose a dynamic interlocked model in which Pros expression in pISCs initiates during the G1 . . .
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