Apical-basal polarity signaling components, lgl1 and apkcs, control glutamatergic synapse number and function

HIGHLIGHTS

• who: John Scott from the Section, Biological Sciences Division, University of California, San Diego, La Jolla, CA, USA have published the paper: Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function, in the Journal: (JOURNAL) of October/25,/2019
• what: 1Neurobiology 2Division 3Department 4Department Here the authors report that conditional knockout of Lgl1 from postnatal day 7 (P7) in hippocampal pyramidal neurons, before the peak of glutamatergic synapse formation, resulted in increased glutamatergic synapse density. The authors show here that a conserved apical-basal polarity signaling component, Lgl1, is localized . . .
  

   

  

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