Apoe targeting strategy in alzheimer’s disease: lessons learned from protective variants

HIGHLIGHTS

• who: Guojun Bu from the (UNIVERSITY) have published the paper: APOE targeting strategy in Alzheimeru2019s disease: lessons learned from protective variants, in the Journal: (JOURNAL)
• what: Along with the common APOE2 variant, these APOE rare protective variants can teach the authors how to target apoE as the authors seek effective ways to prevent and cure AD and other age-related dementias.

SUMMARY

The high prevalence of APOE4 allele frequency (~ 14% in Caucasian non-demented versus ~ 38% in AD) and carrier frequency (~ 20-30% in Caucasian nondemented versus 50-70% in AD . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or E-mail:

If you don't have an account, you can create one here.