Apoe4 associated with severe covid-19 outcomes via downregulation of ace2 and imbalanced ras pathway

HIGHLIGHTS

• who: Feng Chen from the Human ApoE-targeted replacement (ApoE-TR) mice, in which the expression of human ApoE is controlled by the mouse ApoE promoter, where generated on the C BL/, J backgroundThe mouse ApoE gene was replaced by the human ApoE2, Apo, or Apo, gene so that only the human ApoE gene is expressed. ApoE-TR mice were provided by Cyagen Biosciences (ApoE3-TR: , have published the paper: ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway, in the Journal: (JOURNAL) of November/22,/2022
• what: In . . .
  

   

  

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