Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of foxo3a-sod2 pathway

HIGHLIGHTS

  • who: Xiaotong Huang from the Department of Otolaryngology, Yatu2011Sen Memorial, Yat-Sen, Guangzhou, China have published the paper: Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway, in the Journal: (JOURNAL)
  • what: The authors aimed to examine the effect of apoVs treatment on NIHL and its potential mechanism against oxidative stress.
  • how: In this study CBA/J mice were used to establish NIHL model with a 2-h noise exposure which was used in previous studies and proved successful to induce permanent hearing loss . Animal experiments . . .

     

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