Applicability of small-molecule inhibitors in the study of peptidyl arginine deiminase 2 (pad2) and pad4

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  • who: Marı´a Teresa Martı´n Monreal from the melweis University, Hungary France have published the article: Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4, in the Journal: (JOURNAL)
  • what: The authors show in this study that BB-Clamidine is cytotoxic to T_cells, B cells, monocytes, and NK cells when used in concentrations of 1 µM and above, while neither AFM-30a and GSK199 affected cell viability considerably at concentrations up to 20 µM where the inhibitory effect on PAD2 and PAD4 is strong. This study indicates . . .

     

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