Application of perturbation gene expression pro les in drug — from mechanism of action to quantitative modelling

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  • who: . and colleagues from the Pu00e1zmu00e1ny Pu00e9ter Catholic University, Quadram Institute, United Kingdom have published the research work: Application of perturbation gene expression pro les in drug u2014 From mechanism of action to quantitative modelling, in the Journal: (JOURNAL)
  • what: Proteomics and phospho-proteomics are more closely connected to the activity of cellular process than gene_expression, so perturbation proteomics datasets can be used to infer compound effects of signalling and compound similarities (Zhao et_al, 2020; Gabor et_al, 2021). Modelling cellular phenotype One of the main goals of systems biology studies is to develop mechanistically understandable . . .

     

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