Application of second-generation sequencing in congenital pulmonary airway malformations

HIGHLIGHTS

  • who: Gang Zhang from the DepartmentMedical University have published the article: Application of second-generation sequencing in congenital pulmonary airway malformations, in the Journal: Scientific Reports Scientific Reports
  • how: To identify characteristics specific for the CPAM the authors first performed gene set enrichment analysis (GSEA http//u200bwww.u200bbroadu200binstiu200btute.u200borg/u200bgsea/u200bindex.u200bjsp) the results showed that genes related to primary cilium development ciliopathies and cilium assembly were upregulated in CPAM (Fig 1) which highlights that the appearance of primary cilium in the airway of CPAM. The result showed that H3F3A is the most up-regulated . . .

     

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