Application prospects of triphenylphosphine-based mitochondria-targeted cancer therapy

HIGHLIGHTS

  • who: Xiaoxia Cheng and colleagues from the School of Basic Medical Science, Henan University, Kaifeng, China have published the Article: Application Prospects of Triphenylphosphine-Based Mitochondria-Targeted Cancer Therapy, in the Journal: Cancers 2023, 666 of 21/01/2023
  • what: The authors review the various pro-mitochondrial agents that have been developed, particularly the lipophilic cationic triphenylphosphine and discuss the advantages of TPP in mitochondrial targeting functions and the challenges associated with the application of TPP-based mitochondria-targeted anticancer drugs for oncology therapy and mitochondria-targeted drug delivery systems based on lipophilic cations. While . . .

     

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