Applications of quantitative systems pharmacology (qsp) in drug development for nafld and nash and its regulatory application

HIGHLIGHTS

  • who: Scott Q. Siler from the DILIsym Services, a Division of Simulations Plus, u2011862u20116027, Davis Drive, Research Triangle Park, North Carolina, USA have published the paper: Applications of Quantitative Systems Pharmacology (QSP) in Drug Development for NAFLD and NASH and Its Regulatory Application, in the Journal: (JOURNAL) of 24/05/2022
  • what: The use of this approach has grown over the last 20 years, motivating discussions between modelers and regulators to agree upon methodologic standards.
  • future: Mechanistic insights such as this that have been derived from QSP models can help expedite the development . . .

     

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