HIGHLIGHTS
- who: from the Department of RNA Structural Genomics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego, Poznan, Poland have published the Article: Approaches for RNA Structure Characterization, in the Journal: (JOURNAL)
- what: This investigation showed that destabilization of kissingloop contacts results in the observed attenuation of virus growth, but does not affect RNA translation or its stability. After sequencing, bioinformatics analysis is conducted to determine the reactivity of individual nucleotides .
- how: Resulting data showed that replicon-based HTS approach represents useful and reliable tool for drug discovery against ZIKV infection . The obtained . . .
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