Approaches to dose finding in neonates illustrating the variability between neonatal drug development programs

HIGHLIGHTS

  • who: John N. Van den and colleagues from the Division of Clinical Pharmacology, Children`s National Hospital, Washington, DC, USAPediatric Pharmacology and Pharmacometrics Research Center, University Children`s Hospital Basel have published the research: Approaches to Dose Finding in Neonates Illustrating the Variability between Neonatal Drug Development Programs, in the Journal: (JOURNAL)
  • what: In this study, 188 (pre)term infants (28 (range 23-40) weeks GA; 21 days PNA) received meropenem at 20 or 30 mg/kg every 8 or 12 h and 780 meropenem plasma concentrations were analyzed. In this study platelet aggregation in . . .

     

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