Apremilast, a novel phosphodiesterase 4 (pde4) inhibitor, regulates inflammation through multiple camp downstream effectors

HIGHLIGHTS

• who: Miguel Perez-Aso from the concentrations of cytokines were measured by ELISA or by the Luminex platform as described belowAll protocols followed internationally recognized guidelines and were approved by the New York University School of Medicine Institutional Animal Care and Use Committee (NYU SoM, IACUC, protocol number, ). Histology have published the paper: Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors, in the Journal: (JOURNAL)
• what: The aim of this work was to analyze the downstream pathways triggered by apremilast and to test potential interactions of apremilast with MTX . . .
  

   

  

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