Aptamer‐assisted bioconjugation of tyrosine derivatives with hemin/g‐quadruplex (hgq) dnazyme nucleoapzyme nanostructures

HIGHLIGHTS

• who: ChemCatChem and colleagues from the (UNIVERSITY) have published the paper: Aptameru2010Assisted Bioconjugation of Tyrosine Derivatives with hemin/Gu2010quadruplex (hGQ) DNAzyme Nucleoapzyme Nanostructures, in the Journal: (JOURNAL)
• what: At the start of this project, the authors determined the ability of hGQ DNAzymes to conjugate tyrosinamide 1 to azide-functionalized N-methyl luminol (NML) derivative 2, resulting in the formation of tyrosine-NML conjugate 3 ; the azide moiety facilitates future two-step derivatization of NML-Tyr conjugates, e. g., via alkyne-azide click chemistry.
• how: For the quantification of the formed product the authors . . .
  

   

  

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