Ar12 increases bag3 expression which is essential for tau and app degradation via lc3-associated phagocytosis and macroautophagy

HIGHLIGHTS

• who: Paul Dent et al. from the Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USA have published the research work: AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy, in the Journal: (JOURNAL)
• what: The present studies were designed to determine whether LAP / LANDO played a mechanistic role in the abilities of AR12 and neratinib to cause Tau, APP, and chaperone degradation in neurons and microglia.
• future: Future work based on the availability of funding will be required to perform . . .
  

   

  

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