HIGHLIGHTS
- What: By synthesizing data from various observational studies comparing ethinylestradiol with natural estrogens, this analysis seeks to clarify the relative safety profiles of these CHCs and guide clinical practice in contraceptive choice. The authors aim to offer evidence-based recommendations that can inform healthcare providers and users about the safest contraceptive options in terms of VTE risk. Data extraction This systematic review was conducted in accordance with the 2020 Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) as well as PRISMA-Search for literature searches .
- Who: Alessandro Conforti and colleagues from the University of . . .

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