Arginine-containing tripeptides as analgesic substances: the possible mechanism of ligand-receptor binding to the slow sodium channel

HIGHLIGHTS

  • who: Ilya V. Rogachevskii and colleagues from the Pavlov Institute of Physiology of the Russian Academy of Sciences, Saint Petersburg, Russia have published the article: Arginine-Containing Tripeptides as Analgesic Substances: The Possible Mechanism of Ligand-Receptor Binding to the Slow Sodium Channel, in the Journal: (JOURNAL) of 26/05/2022
  • what: The aim of this study is to elucidate the molecular mechanism of ligandreceptor binding of short arginine-containing peptides to the slow sodium NaV 1.8 channel that is responsible for the primary sensory coding of nociceptive signals . In accordance with the hypothesis . . .

     

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