Arginine glycosylation enhances methylglyoxal detoxification

HIGHLIGHTS

  • who: Samir El Qaidi from the CollegeState University have published the paper: Arginine glycosylation enhances methylglyoxal detoxification, in the Journal: Scientific Reports Scientific Reports of 20/01/2021

SUMMARY

    The authors found that SseK1 is active within Salmonella enterica and that it glycosylates GloA, GloB, GloC, and YajL on arginine residues to significantly enhance their enzymatic activities and provide increased resistance to MGO. The authors then immunoblotted protein lysates for R-GlcNAc on each protein and observed that the type I glyoxalase GloA, the type II glyoxalase isomers GloB and GloC, and the . . .

     

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