Arid1a-dependent maintenance of h3.3 is required for repressive chd4-zmynd8 chromatin interactions at super-enhancers

HIGHLIGHTS

• who: Jake J. Reske from the (UNIVERSITY) have published the research work: ARID1A-dependent maintenance of H3.3 is required for repressive CHD4-ZMYND8 chromatin interactions at super-enhancers, in the Journal: (JOURNAL) of 25/04/2022
• what: The authors investigate the function of ARID1A a subunit of certain mammalian SWI/SNF chromatin remodeling complexes associated with malignancies and benign diseases originating from the uterine endometrium. Through genome-wide analysis of human endometriotic epithelial cells the authors show that more than half of ARID1A binding sites are marked by the variant histone H3.3 including . . .
  

   

  

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