Artemisinin relieves osteoarthritis by activating mitochondrial autophagy through reducing tnfsf11 expression and inhibiting pi3k/akt/mtor signaling in cartilage

HIGHLIGHTS

  • who: Jin Li from the Department of Orthopedic Hospital of Jiaxing University, Jiaxing, China have published the paper: Artemisinin relieves osteoarthritis by activating mitochondrial autophagy through reducing TNFSF11 expression and inhibiting PI3K/AKT/mTOR signaling in cartilage, in the Journal: (JOURNAL)
  • what: The study showed that AT alleviates OA by regulating mitou2011 chondrial autophagy. This study explored whether AT treatment alleviates IL-1u03b2-induced chondrocyte production in_vivo and in_vitro. AT alleviated cartilage degradation and the defection of autophagy in rat OA models Given the findings of AT in_vitro, a rat OA model was developed to . . .

     

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