HIGHLIGHTS
- who: Oliver Rossbach from the (UNIVERSITY) have published the Article: Artificial Circular RNA Sponges Targeting MicroRNAs as a Novel Tool in Molecular Biology, in the Journal: (JOURNAL)
- what: The authors used 50 times less circRNA in the experiments compared to Liu et_al11 when transfecting a similar bulged binding_site and found this amount sufficient to reduce HCV protein translation to nondetectable levels .
SUMMARY
Transfection of the circRNA targeting miRNA-21 was demonstrated to inhibit gastric cancer cell proliferation in culture to increase apoptosis and dysregulate global protein expression. The usage of this . . .
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