HIGHLIGHTS
- who: ARumenamide et al. from the University of Bari Aldo Moro, Italy have published the paper: ARumenamides : A novel class of potential antiarrhythmic compounds, in the Journal: (JOURNAL)
- what: The authors used virtual docking and whole-cell patch clamp to assess the efficacy of a new class of compounds, ARumenamide (AR), that dock within the fenestrations, in an effort to target LoF.
SUMMARY
His prediction was correct, and structural and electrophysiological studies proved that bulky drugs, especially ones like flecainide elicit their statedependent effects on Nav via the fenestrations (Kaczmarski and . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.