HIGHLIGHTS
- who: Aude Jacob and colleagues from the (UNIVERSITY) have published the research work: Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels, in the Journal: (JOURNAL)
- what: Effect of DEP exposure on Cyp1b1 expression in isolated rat brain microvessels Since Cyp1a1 was not detected at the protein level after TCDD exposure, the authors focused on AhR-dependent regulation of Cyp1b1 in the following studies. The authors show that exposing rat brain microvessels to DEP for 6 h ex vivo increased Cyp1b1 protein in a concentration-dependent manner . . .
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