HIGHLIGHTS
- who: Top from the Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA have published the paper: As expected, based on rapamycin-like p53-mediated gerosup-, in the Journal: (JOURNAL) of August/25,/2022
SUMMARY
In fact, rapamycin and anything that inhibits mTOR such as serum-starvation, contact inhibition and anoxia partially suppresses geroconversion and the senescent phenotype (see for ref ). Since mutant p53 (p53-3KR) cannot cause cell-cycle arrest, it cannot cause senescence either. On another hand, Recent work by Gu and co-workers (Kon et_al, published in 2021), entitled "mTOR inhibition . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.