Asgr1: an emerging therapeutic target in hypercholesterolemia

HIGHLIGHTS

• who: Wenqi Zhao from the DepartmentUniversity of Science and Technology of China, Hefei, China have published the research work: ASGR1: an emerging therapeutic target in hypercholesterolemia, in the Journal: (JOURNAL) of 19/08/2022
• what: Another advantage of cholesterol-lowering effects delivered by ASGR1 inhibition is that this approach has the potential to work in synergy with other cholesterol-lowering pathways.
• how: In the study by Wang et_al1 the results showed that ASGR1 binds and delivers asialoglycoproteins to lysosomes via clathrinmediated endocytosis subsequently amino_acids released from glycoprotein breakdown by lysosomes activate lysosomal mTORC1 . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.